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Showing posts from June, 2008

Fungal Etiology of Inflammatory Bowel Disease

Crohn’s disease and ulcerative colitis, although distinguished by well-known characteristics, are collectively known as inflammatory bowel diseases (IBD). IBD is characterized by a host of symptoms such as diarrhea, abdominal cramps, rectal bleeding, weight loss, fever, and a host of extra-intestinal symptoms, including disorders of the eyes, liver, gallbladder, muscles and joints, kidneys, and skin. The treatments usually focus on relief of symptoms with anti-inflammatory drugs or surgery (i.e. removal of the affected part of the intestines).    The cause of IBD remains "unknown." Some have implicated a viral etiology to IBD. In the medical journal The Lancet, Dr. Wakefield and colleagues found that three of four offspring in mothers that had measles during pregnancy developed severe Crohn’s later in life. Of note is that recurrent antibiotic-resistant pneumonia preceded the Crohn’s in every case. This is important because antibiotics are known to increase the risk of fun...